multtest

Resampling-based multiple hypothesis testing

Non-parametric bootstrap and permutation resampling-based multiple testing procedures for controlling the family-wise error rate (FWER), generalized family-wise error rate (gFWER), tail probability of the proportion of false positives (TPPFP), and false discovery rate (FDR). Single-step and step-wise methods are implemented. Tests based on a variety of t- and F-statistics (including t-statistics based on regression parameters from linear and survival models) are included. Results are reported in terms of adjusted p-values, confindence regions and test statistic cutoffs. The procedures are directly applicable to identifying differentially expressed genes in DNA microarray experiments.

Author Katherine S. Pollard, Yongchao Ge, Sandrine Dudoit
Maintainer Katherine S. Pollard

Vignettes (Documentation)

Package Downloads

MTPALL.pdf
MTP.pdf
multtest.pdf
Source multtest_1.12.0.tar.gz
Windows binary multtest_1.12.0.zip
OS X binary multtest_1.12.0.tgz

Details

biocViews
Depends R, methods, Biobase, survival
Suggests
Imports
SystemRequirements
License LGPL
URL
dependsOnMe ABarray, aCGH, adSplit, globaltest, LMGene, OCplus, SAGx, siggenes, webbioc
suggestsMe annaffy, ecolitk, GlobalAncova, GOstats, pcot2, safe, vsn, xcms